| February |
| | 4 | 9:00AM | Simpson | vs. | University of British Columbia | 8-0 | |
| | Lancers Invitational - Riverside, California |
| | | 11:00AM | Bethany | @ | California Baptist University | 1-14 | |
| | Lancers Invitational - Riverside, California |
| | | 1:00PM | Simpson | @ | California Baptist University | 2-8 | |
| | Lancers Invitational - Riverside, California |
| | | 3:00PM | Bethany | vs. | University of British Columbia | 1-6 | |
| | Lancers Invitational - Riverside, California |
| | | 3:00PM | Simpson | @ | Azusa Pacific University | 4-6 | |
| | | Game 2 | Simpson | @ | Azusa Pacific University | 2-3 | |
| | 5 | 9:00AM | Bethany | vs. | Simpson | 1-2 | |
| | Lancers Invitational - Riverside, California |
| | | 1:00PM | Bethany | @ | California Baptist University | RAIN | |
| | Lancers Invitational - Riverside, California |
| | | 3:00PM | Simpson | vs. | University of British Columbia | 7-6 | |
| | Lancers Invitational - Riverside, California |
| | 6 | | Bethany | vs. | TBA | RAIN | |
| | Lancers Invitational - Riverside, California (Championship/Consolation) |
| | | | Simpson | vs. | TBA | RAIN | |
| | Lancers Invitational - Riverside, California (Championship/Consolation) |
| | | 10:00AM | Simpson | vs. | University of British Columbia | RAIN | |
| | Lancers Invitational - Riverside, California (2/3 Game) |
| | | 12:30PM | Bethany | @ | California Baptist University | RAIN | |
| | Lancers Invitational - Riverside, California (1/4 Game) |
| | 12 | | Bethany | @ | Patten University | 1-3 | |
| | Hayward, California |
| | | Game 2 | Bethany | @ | Patten University | 4-1 | |
| | | 9:00AM | Corban University | @ | Simpson | 1-8 | |
| | Big League Dreams Classic - Redding, California |
| | | 9:00AM | Menlo | vs. | Northwest Christian University | 0-10 | |
| | Big League Dreams Tournament - Redding, Calif. |
| | | 11:00AM | William Jessup | vs. | Point Loma Nazarene University | 0-8 | |
| | Big League Dreams Classic - Redding, California |
| | | 11:00AM | Biola University | @ | Simpson | 5-7 | |
| | Big League Dreams Classic - Redding, California |
| | | 1:00PM | William Jessup | vs. | Corban University | 3-10 | |
| | Big League Dreams Classic - Redding, California |
| | | 3:00PM | William Jessup | vs. | Biola University | 8-1 | |
| | Big League Dreams Classic - Redding, California |
| | | 3:00PM | Menlo | vs. | Corban University | 8-15 | |
| | Big League Dreams Classic - Redding, California |
| | 13 | 11:00AM | California Baptist University | @ | Simpson | 8-0 | |
| | Big League Dreams Classic - Redding, California |
| | | 11:00AM | William Jessup | vs. | Northwest Christian University | 4-1 | |
| | Big League Dreams Classic - Redding, California |
| | | 11:00AM | Simpson | vs. | California Baptist University | 0-3 | |
| | Big League Dreams Classic - Redding, California |
| | | 11:00AM | Menlo | vs. | Oregon Institute of Technology | 10-9 | |
| | Big League Dreams Tournament - Redding, Calif. |
| | | 12:00PM | Holy Names | @ | Patten University | 9-2 | |
| | Game will be played at Standley Field - Hayward. |
| | | 1:00PM | Menlo | vs. | Biola University | 1-8 | |
| | Big League Dreams Tournament - Redding, Calif. |
| | | 1:00PM | William Jessup | vs. | Northwest Christian University | 2-1 | |
| | Big League Dreams Classic - Redding, California |
| | | 2:00PM | Holy Names | @ | Patten University | 4-2 | |
| | Game will be played at Standley Field - Hayward. |
| | | 3:00PM | Oregon Institute of Technology | @ | Simpson | 5-2 | |
| | Big League Dreams Classic - Redding, California |
| | | 3:00PM | William Jessup | vs. | California Baptist University | 0-12 | |
| | Big League Dreams Classic - Redding, California |
| | | 5:00PM | Point Loma Nazarene University | @ | Simpson | 4-0 | |
| | Big League Dreams Classic - Redding, California |
| | 15 | 12:00PM | Point Loma Nazarene University | vs. | Holy Names | 10-1 | |
| | Game will be played at CSU, East Bay |
| | | 2:00PM | Point Loma Nazarene University | vs. | Holy Names | 4-3 | (8) |
| | Game will be played at CSU, East Bay |
| | 17 | 3:00PM | William Jessup | @ | Academy of Art University | 6-7 | |
| | Mission Blue Softball Field - Brisbane, California |
| | | Game 2 | William Jessup | @ | Academy of Art University | 8-6 | |
| | 19 | 12:00PM | Holy Names | vs. | California State University-San Marcos | 2-8 | |
| | Southern California Smash Tournament @ California Baptist University |
| | | 5:00PM | Holy Names | @ | California Baptist University | 0-14 | |
| | Southern California Smash Tournament @ California Baptist University |
| | 20 | 12:00PM | Holy Names | vs. | California State University-San Marcos | 0-14 | |
| | Southern California Smash Tournament @ California Baptist University |
| | | 12:00PM | Academy of Art University | @ | Menlo | 7-1 | |
| | | Game 2 | Academy of Art University | @ | Menlo | 4-1 | |
| | | 1:00PM | Southern Oregon | @ | Simpson | 2-6 | |
| | | Game 2 | Southern Oregon | @ | Simpson | 0-1 | |
| | | 2:30PM | Holy Names | @ | California Baptist University | 1-9 | |
| | Southern California Smash Tournament @ California Baptist University |
| | 21 | 11:00AM | Holy Names | @ | Concordia University | 0-2 | |
| | | 1:00PM | Holy Names | @ | Concordia University | 0-12 | |
| | 24 | 12:30PM | Hope International University | @ | Menlo | 9-4 | |
| | at Red Morton Community Park, McGarvey Field - Redwood City, Calif. |
| | 25 | 4:00PM | William Jessup | vs. | Hope International University | 0-2 | |
| | SOU Invitational - Medford, Oregon |
| | | 4:00PM | Holy Names | @ | Southern Oregon | 0-1 | |
| | SOU Tournament - US Cellular Fields - Field 1 |
| | | 6:00PM | Simpson | vs. | Azusa Pacific University | 2-1 | |
| | SOU Invitational - Medford, Oregon |
| | | 6:00PM | William Jessup | vs. | Concordia University | 1-2 | |
| | SOU Invitational - Medford, Oregon |
| | 26 | 9:00AM | Holy Names | @ | Concordia University | 1-3 | |
| | SOU Tournament - US Cellular Fields - Field 3 |
| | | 11:00AM | Simpson | vs. | William Jessup | 4-6 | |
| | SOU Invitational - Medford, Oregon |
| | | 11:00AM | Holy Names | vs. | Oregon Institute of Technology | 3-5 | |
| | SOU Tournament - US Cellular Fields - Field 2 |
| | | 1:00PM | William Jessup | vs. | Northwest Christian University | 6-5 | |
| | SOU Invitational - Medford, Oregon |
| | | 1:00PM | Simpson | vs. | Biola University | 2-1 | |
| | SOU Invitational - Medford, Oregon |
| | | 3:00PM | Holy Names | @ | Biola University | 2-6 | |
| | SOU Tournament - US Cellular Fields - Field 1 |
| | 27 | 9:00AM | William Jessup | vs. | Azusa Pacific University | 6-4 | |
| | SOU Invitational - Medford, Oregon |
| | | 11:00AM | Holy Names | @ | Northwest Christian University | 10-11 | |
| | SOU Tournament - US Cellular Fields - Field 4 |
| | | 11:00AM | Simpson | vs. | Hope International University | 2-0 | |
| | SOU Invitational - Medford, Oregon |
| | | 1:00PM | Holy Names | @ | Southern Oregon | 8-11 | |
| | SOU Tournament - US Cellular Fields - Field 1 |
| | | 1:00PM | Simpson | vs. | Concordia University | 8-7 | |
| | SOU Invitational - Medford, Oregon |
| March |
| | 3 | Game 2 | Holy Names | @ | Academy of Art University | RAIN | |
| | | 3:00PM | Holy Names | @ | Academy of Art University | RAIN | |
| | Mission Blue Softball Field - Brisbane, California |
 | 5 | 12:00PM | Bethany | @ | William Jessup | 0-2 | |
| | | Game 2 | Bethany | @ | William Jessup | 0-5 | |
| | | 1:00PM | Menlo | @ | Simpson | 2-11 | |
| | | Game 2 | Menlo | @ | Simpson | 0-2 | |
| | 6 | 12:00PM | Bethany | @ | Simpson | 0-2 | |
| | | Game 2 | Bethany | @ | Simpson | 3-4 | |
| | | 12:00PM | Menlo | @ | William Jessup | 0-11 | |
| | | Game 2 | Menlo | @ | William Jessup | 1-6 | |
| | 8 | 1:30PM | Bethany | @ | Concordia University | 0-2 | |
| | | Game 2 | Bethany | @ | Concordia University | 0-14 | (5) |
| | 9 | 10:00AM | Penn State Abington | vs. | Holy Names | 0-16 | (5) |
| | Sun West Tournament - Hart Park Field #3 |
| | | 2:00PM | Holy Names | vs. | Concordia Illinois | 8-0 | |
| | Sun West Tournament - Hart Field Park #2 |
| | 10 | 10:00AM | Holy Names | vs. | Penn State Abington | 15-0 | |
| | Sun West Tournament - Hart Park Field #2 |
| | | 12:00PM | Holy Names | vs. | DeSales University | 4-3 | |
| | Sun West Tournament - Hart Park Field #2 |
| | | 12:00PM | Menlo | @ | Occidental College | 7-6 | |
| | | Game 2 | Menlo | @ | Occidental College | 10-5 | |
| | | 2:00PM | Bethany | @ | Vanguard University | 4-5 | |
| | | Game 2 | Bethany | @ | Vanguard University | 0-3 | |
| | 11 | 12:00PM | Holy Names | vs. | Wheaton College | 3-1 | |
| | Sun West Tournament - Hart Park Field #2 |
| | | 2:00PM | Holy Names | vs. | Chapman University | 7-6 | |
| | Sun West Tournament - Hart Park Field #3 |
| | | 2:00PM | Menlo | @ | Whittier College | 6-8 | |
| | | Game 2 | Menlo | @ | Whittier College | 8-11 | |
| | | 4:00PM | Bethany | @ | Azusa Pacific University | 0-2 | |
| | | Game 2 | Bethany | @ | Azusa Pacific University | 2-10 | (5) |
| | 12 | 10:00AM | Holy Names | vs. | DeSales University | 5-6 | (8) |
| | Sun West Tournament - Hart Park Field #3 |
| | | 1:00PM | Menlo | @ | Hope International University | 2-6 | |
| | | 2:00PM | Holy Names | vs. | Suffolk University | 11-1 | |
| | Sun West Tournament - Hart Park Field #2 |
| | 13 | 11:00AM | William Jessup | @ | Southern Oregon | 10-1 | |
| | | Game 2 | William Jessup | @ | Southern Oregon | 9-3 | |
| | | 12:00PM | Bethany | @ | California State University-San Marcos | 1-8 | |
| | | Game 2 | Bethany | @ | California State University-San Marcos | 0-9 | |
| | | 12:00PM | Menlo | @ | Pomona-Pitzer | 2-10 | |
| | | Game 2 | Menlo | @ | Pomona-Pitzer | 8-9 | |
| | 14 | | Simpson | @ | Northwest Christian University | 1-0 | |
| | | Game 2 | Simpson | @ | Northwest Christian University | 6-1 | |
| | 15 | 1:00PM | Simpson | @ | Corban University | 3-6 | |
| | | Game 2 | Simpson | @ | Corban University | 5-3 | |
| | 20 | 12:00PM | Holy Names | @ | Bethany | 17-0 | |
| | | Game 2 | Holy Names | @ | Bethany | 6-2 | |
| | | 2:00PM | Simpson | @ | William Jessup | 8-1 | |
| | | Game 2 | Simpson | @ | William Jessup | 2-1 | |
| | 21 | 12:00PM | Menlo | @ | Holy Names | 0-10 | |
| | Game will be played @ Thrasher Park in San Leandro |
| | | Game 2 | Menlo | @ | Holy Names | 0-5 | |
| | | 1:00PM | Eastern Oregon University | @ | Simpson | 2-3 | |
| | | Game 2 | Eastern Oregon University | @ | Simpson | 6-3 | |
| | 22 | 1:00PM | Oregon Institute of Technology | @ | William Jessup | 2-3 | |
| | | Game 2 | Oregon Institute of Technology | @ | William Jessup | 3-5 | |
| | 23 | 1:00PM | Eastern Oregon University | @ | Menlo | 2-1 | |
| | | Game 2 | Eastern Oregon University | @ | Menlo | 0-5 | |
| | 24 | 1:00PM | Eastern Oregon University | @ | William Jessup | 0-4 | |
| | | Game 2 | Eastern Oregon University | @ | William Jessup | 0-8 | (6) |
| | 26 | 12:00PM | Patten University | @ | Simpson | 0-7 | |
| | | Game 2 | Patten University | @ | Simpson | 4-12 | |
| | 27 | 12:00PM | William Jessup | @ | Patten University | 0-2 | |
| | Hayward, California |
| | | Game 2 | William Jessup | @ | Patten University | 9-4 | |
| | | 12:00PM | Bethany | @ | Menlo | 2-1 | (8) |
| | | Game 2 | Bethany | @ | Menlo | 4-9 | |
| | | 12:00PM | Simpson | @ | Holy Names | 3-1 | |
| | Game will be played @ Thrasher Park in San Leandro |
| | | Game 2 | Simpson | @ | Holy Names | 2-0 | |
| | 29 | 2:00PM | Simpson | @ | California State University-San Marcos | 1-8 | |
| | | Game 2 | Simpson | @ | California State University-San Marcos | 1-2 | |
| | 30 | 1:00PM | William Jessup | @ | Vanguard University | 0-2 | |
| | | Game 2 | William Jessup | @ | Vanguard University | 4-0 | |
| | 31 | 1:00PM | St. Catherine University | @ | Bethany | 3-2 | |
| | | Game 2 | St. Catherine University | @ | Bethany | 1-10 | |
| | | 1:00PM | William Jessup | @ | Concordia University | 0-4 | |
| | | Game 2 | William Jessup | @ | Concordia University | 0-3 | |
| | | 2:00PM | Simpson | @ | Vanguard University | 1-11 | |
| | | Game 2 | Simpson | @ | Vanguard University | 0-3 | |
| April |
| | 1 | 1:00PM | California State University-San Marcos | @ | Bethany | 8-0 | |
| | | Game 2 | California State University-San Marcos | @ | Bethany | 12-1 | |
| | | 1:00PM | William Jessup | @ | Hope International University | 5-2 | |
| | Craig Park - Fullerton, California |
| | | Game 2 | William Jessup | @ | Hope International University | 3-4 | |
| | | 1:00PM | St. Catherine University | @ | Menlo | 7-3 | |
| | | Game 2 | St. Catherine University | @ | Menlo | 0-5 | |
| | | 2:00PM | Simpson | @ | Concordia University | 1-6 | |
| | | Game 2 | Simpson | @ | Concordia University | 3-0 | |
| | 2 | 11:00AM | William Jessup | @ | California Baptist University | 0-10 | |
| | Game 1 of double header |
| | | Game 2 | William Jessup | @ | California Baptist University | 0-1 | |
| | | 12:00PM | University of Great Falls | @ | Holy Names | RAIN | |
| | Game will be played @ Thrasher Park in San Leandro |
| | | Game 2 | University of Great Falls | @ | Holy Names | RAIN | |
| | 3 | 12:00PM | University of Great Falls | @ | Bethany | 7-8 | (9) |
| | | Game 2 | University of Great Falls | @ | Bethany | 1-2 | (8) |
| | 7 | 4:00PM | William Jessup | @ | Holy Names | 2-3 | (9) |
| | Game will be played @ Thrasher Park in San Leandro |
| | | Game 2 | William Jessup | @ | Holy Names | 2-6 | |
| | 9 | 1:00PM | Simpson | @ | Bethany | 9-1 | |
| | | Game 2 | Simpson | @ | Bethany | 4-1 | |
| | | 1:00PM | William Jessup | @ | Menlo | 9-1 | |
| | | Game 2 | William Jessup | @ | Menlo | 15-2 | |
| | 10 | 12:00PM | William Jessup | @ | Bethany | 7-2 | |
| | | Game 2 | William Jessup | @ | Bethany | 14-0 | |
| | | 12:00PM | Simpson | @ | Menlo | 3-2 | |
| | | Game 2 | Simpson | @ | Menlo | 11-0 | |
| | | 1:00PM | Patten University | @ | Holy Names | 2-7 | |
| | Game will be played @ Thrasher Park in San Leandro |
| | | Game 2 | Patten University | @ | Holy Names | 2-7 | |
| | 14 | 1:00PM | Patten University | @ | William Jessup | 3-2 | |
| | | Game 2 | Patten University | @ | William Jessup | 2-10 | |
| | | 1:00PM | Holy Names | @ | Academy of Art University | 3-4 | (8) |
| | | Game 2 | Holy Names | @ | Academy of Art University | 2-1 | |
| | 16 | 1:00PM | Patten University | @ | Bethany | 4-2 | |
| | | Game 2 | Patten University | @ | Bethany | 0-2 | |
| | 17 | 12:00PM | Holy Names | @ | Menlo | 8-0 | |
| | | Game 2 | Holy Names | @ | Menlo | 6-1 | |
| | | 1:00PM | William Jessup | @ | Simpson | 5-2 | |
| | | Game 2 | William Jessup | @ | Simpson | 2-6 | |
| | 18 | 12:00PM | Bethany | @ | Holy Names | 0-3 | |
| | Game will be played @ Thrasher Park in San Leandro |
| | | Game 2 | Bethany | @ | Holy Names | 3-5 | |
| | 22 | 2:00PM | California State University-East Bay | @ | Menlo | 5-4 | |
| | | Game 2 | California State University-East Bay | @ | Menlo | 3-1 | |
| | 23 | 1:00PM | Patten University | @ | Simpson | 1-2 | |
| | | Game 2 | Patten University | @ | Simpson | 3-14 | |
| | 24 | 12:00PM | Menlo | @ | Bethany | 4-5 | (8) |
| | | Game 2 | Menlo | @ | Bethany | 2-3 | (8) |
| | | 2:00PM | Holy Names | @ | William Jessup | 2-0 | (8) |
| | | Game 2 | Holy Names | @ | William Jessup | 0-5 | |
| | 25 | 2:00PM | Holy Names | @ | Simpson | 6-1 | |
| | | Game 2 | Holy Names | @ | Simpson | 5-6 | (10) |
| | 30 | 12:00PM | University of Great Falls | @ | Simpson | 7-8 | |
| | NAIA Qualifier - Redding, California |
| | | 1:00PM | Holy Names | vs. | University of Great Falls | 6-3 | |
| | NAIA Qualifer - Redding, California |
| | | 4:00PM | Holy Names | @ | Simpson | 1-0 | |
| | NAIA Qualifier - Redding, California |
| May |
| | 1 | 2:00PM | Holy Names | @ | Simpson | 4-1 | |
| | NAIA Qualifier - Redding, California |
| | 13 | 1:00PM | Simpson | vs. | Oakland City University | 6-0 | |
| | 2010 NCCAA Softball National Tournament - Palm Beach Gardens, Florida |
| | 14 | 11:00AM | Simpson | vs. | Central Baptist College | 4-5 | |
| | 2010 NCCAA Softball National Tournament - Palm Beach Gardens, Florida |
| | | 1:00PM | Simpson | vs. | Judson University | 5-2 | |
| | 2010 NCCAA Softball National Tournament - Palm Beach Gardens, Florida |
| | | 3:30PM | Simpson | vs. | Olivet Nazarene University | 2-3 | |
| | 2010 NCCAA Softball National Tournament - Palm Beach Gardens, Florida |
| | 20 | 7:00AM | Holy Names | vs. | Olivet Nazarene University | 3-9 | |
| | 2010 NAIA Softball National Championship - Decatur, Alabama |
| | 22 | 10:30AM | Holy Names | vs. | California Baptist University | 5-13 | |
| | 2010 NAIA Softball National Championship - Decatur, Alabama |
| | 24 | 9:30AM | Holy Names | vs. | Midland Lutheran College | 1-0 | |
| | 2010 NAIA Softball National Championship - Decatur, Alabama |
